Natural Products
| Catalog No. | Information |
| CFN92790 | 6(1H)-Azulenone, 2,3-dihydro-1,4-dimethyl Reference standards. |
| CFN92791 | Aeruginolactone Standard reference |
| CFN92792 | Curculigoside C Standard reference |
| CFN92793 | Benzyl 2,6-dimethoxybenzoate Benzyl 2,6-dimethoxybenzoate shows significant analgesic effects, it induces a concentration-dependent inhibition of the spontaneous contractions of the guinea-pig ileum with IC50 values ranging from 1.49 to 4.96 microM. Benzyl 2,6-dimethoxybenzoate shows antimicrobial activity against several bacteria (S. aureus, E. coli, P. aeruginosa, and B. subtilis) and fungi (C. albicans and T. mentagrophytes). |
| CFN90558 | Malic acid Malic acid is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtue of its capacity to induce these effects. |
| CFN90559 | 4-Methoxycinnamaldehyde 4-Methoxycinnamaldehyde can inhibit human respiratory syncytial virus(RSV) in a human larynx carcinoma cell line, it may be helpful to manage the disease induced by RSV infection. trans-4-Methoxycinnamaldehyde shows potent nematicidal activity. |
| CFN90560 | alpha-Solanine Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut. Alpha-Solanine has proliferation-inhibiting and apoptosis-promoting effect on multiple cancer cells, such as clone, liver, melanoma cancer cells. |
| CFN00450 | alpha-Chaconine Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects. |
| CFN92794 | Isoderrone Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabetes. |
| CFN92795 | Yukovanol Yukovanol inhibits the proliferation of activated HSC-T6 cells in vitro. |
| CFN92796 | (20R)-Ginsenoside Rh1 (20R)-Ginsenoside Rh1 exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer. |
| CFN92797 | Panaxydol Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MAPK activation, cAMP, MAP kinase and ROS generation through NADPH oxidase and mitochondria. It induces the differentiation in C6 cells, may through a PI 3-K-dependent pathway. |
| CFN92798 | Panaxydiol Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM. |
| CFN92799 | cis-Khellactone cis-Khellactone is a natural product from Angelica sinensis. |
| CFN92800 | Qianhucoumarin G Qianhucoumarin G is a natural product from Peucedanum praeruptorum. |
| CFN92801 | Inulanolide A Inulanolide A is a novel NFAT1 and MDM2 dual targeting agent and may be a clinical candidate for breast cancer therapy. Inulanolide A has potent cytotoxicity. |
| CFN92802 | 14-Deoxyandrographolide 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A. |
| CFN92803 | Delta3,2-Hydroxylbakuchiol Delta3,2-Hydroxylbakuchiol, a monoamine transporter inhibitor involved in regulating dopaminergic and noradrenergic neurotransmission and may have represented potential pharmacotherapies for disorders such as Parkinson's disease, depression, and cocaine addiction. |
| CFN92804 | Psoracorylifol C Psoracorylifol C is a natural product from Psoralea corylifolia Linn. |
| CFN92805 | 4,4'-Di-O-methylellagic acid 4,4'-di-O-methylellagic acid is the most effective compound in the inhibition of colon cancer cell proliferation. |
| CFN92806 | 3,4'-Di-O-methylellagic acid Reference standards. |
| CFN92807 | Glucopyranoside,(3beta,25R)-17-hydroxyspirost-5-en-3-yl Reference standards. |
| CFN92808 | Ombuoside Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays. |
| CFN92809 | Isosakuranin Isosakuranin is a product from Paliurus ramosissimus. |
| CFN92810 | Dihydrosanguinarine Dihydrosanguinarine has antifungal and anticancer activity.Dihydrosanguinarine at concentrations from 5 microM induced primarily necrosis, whereas apoptosis occurred at 10 microM and above. Dihydrosanguinarine has potential application in the therapy of serious infection caused by I. multifiliis. |
| CFN92811 | Norsanguinarine Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, A549, and HT-29 cell lines. |
| CFN92812 | Stylopine Stylopine can serve as a model compound for the design and future development of structurally related AKR1C3 inhibitors. It suppresses the NO and PGE2 production in macrophages by inhibiting the iNOS and COX-2 expressions, may contribute to the anti-inflammatory activity of Chelidonium majus. |
| CFN92813 | Ginsenoside Rs3 Ginsenoside Rs3 induce apoptosis, is related to the elevations of p53 and p21WAF1 in the cells. |
| CFN92814 | Pseudolaric acid A Pseudolaric acid A and -B can inhibit the growth of particular cell type. |
| CFN92815 | Chamaechromone Chamaechromone has anti-HBV and insecticidal activity. The hydroxylation of Chamaechromone is inhibited by α-naphthoflavone, and predominantly catalyzed by recombinant human cytochrome P450 1A2. |
| CFN92816 | Epinortrachelogenin Standard reference |
| CFN92817 | Gamma-Tocotrienol Gamma-Tocotrienol has antioxidant activity, it as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. Gamma-Tocotrienol is a novel blocker of the STAT3 activation pathway, it can induce the apoptosis on human gastric cancer SGC-7901 cells via mitochondria-dependent apoptosis pathway, with a potential role in future therapies for HCC and other cancers. |
| CFN92818 | Ginsenoside Rk2 Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. |
| CFN92819 | Bayogenin methyl ester Reference standards. |
| CFN92820 | 3-Oxopomolic acid methyl ester Reference standards. |
| CFN92821 | Alpha-Tocotrienol Alpha-Tocotrienol supplementation counteracts the lipid peroxidation but not the barrier perturbation in the stratum corneum (SC) induced by 10% benzoyl peroxide (BPO). It can exert anti-apoptotic neuroprotective action independently of its antioxidant property. Alpha-Tocotrienol inhibits osteoclastic bone resorption by suppressing RANKL expression and signaling and bone resorbing activity. |
| CFN92822 | Beta-Tocotrienol Beta-Tocotrienol to serve as a new anticancer agent for treating human lung and brain cancers. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations. |
| CFN97865 | Eriodictyol-7-O-glucoside Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC; it also can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CFN90600 | Onjisaponin B Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease. Onjisaponins may provide safe and potent adjuvants for intranasal inoculation of influenza HA and DPT vaccines. |
| CFN92823 | Phorbol Phorbol is a natural product from Euphorbia pekinensis Rupr. |
| CFN92824 | Notoginsenoside T5 Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been used in traditional Chinese medicine to treat atherosclerosis;TPNS can prevent atherosclerosis by lowering serum lipid levels and regulating vascular CD40 and MMP-9 expression, TPNS may have implications for clinical treatment of atherosclerosis vascular disease. |
| CFN92825 | Parkeol Reference standards. |
| CFN92826 | Cis-N-Feruloyltyramine Cis-N-Feruloyltyramine shows cytotoxicity against the P-388 cancer cell line. N-cis-Feruloyltyramine and N-trans-Feruloyltyramine are the inhibitors of in vitro prostaglandin (PG) synthesis. |
| CFN92827 | Leptocarpinine Standard reference |
| CFN92828 | Dihydrobonducellin Dihydrobonducellin has immunopharmacological activity, it significantly inhibits the production of IL-2 and IFN-gamma in activated PBMC in a concentration-dependent manner. |
| CFN92829 | 3-Galloylquinic acid Theogallin(3-Galloylquinic acid ), its derivatives, its metabolite quinic acid, the derivatives thereof, its metabolites or the pharmaceutically acceptable salts of said substances can be used for producing a drug for use in the prophylaxis or treatment of neurological and psychiatric diseases of the central nervous system, especially of dementia such as Alzheimer's disease or Parkinson's disease, of depressions and concentration disorders such as attention deficit hyperactivity disorder.L-theanine- and theogallin-enriched decaffeinated green tea extract are able to change the physiological pattern of electrical hippocampus activity in a concentration dependent manner (EC50=3mg/L), they can improve cognition at concomitant mental relaxation in man. Theogallin also has scavenging radical activity. |
| CFN92830 | 4-Galloylquinic acid 4-Galloylquinic acid shows some antioxidative activity. |
| CFN92831 | Digitonin Digitonin can increase cell permeability by binding to cholesterol molecules and reduce tumor growth. Digitonin solubilizes mitochondrial membrane, breaks the integrity of the respiratory chain and releases two mobile redox-active components: coenzyme Q (CoQ) and cytochrome c (cyt c). |
| CFN92832 | Sappanol Sappanol inhibits lipid peroxidation in a concentration-dependent manner, can significantly attenuated H2O2-induced retinal death, can be potential antioxidant treatment for retinal diseases. |
| CFN92833 | 3-Deoxysappanchalcone 3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level. 3-Deoxysappanchalcone has anti-inflammatory, and anti-influenza virus activities, the mechanism involved anti-apoptosis and anti-inflammation activities in vitro. It has inhibitory activity on MMP-9 expression and production in TNF-α-treated cells, is mediated by the suppression of AP-1 and NF-κB activation. |
