Natural Products
| Catalog No. | Information |
| CFN97732 | 27-Hydroxymangiferonic acid 27-Hydroxymangiferonic acid is a natural product from Mangifera indica. |
| CFN97733 | Totarol Totarol has anti-bacteria effect by restraining bacterial growth by perturbing the cell division and proliferation, including several pathogenic Gram-positive bacteria, mycobacterium tuberculosis. Totarol treatment leads to metabolic shutdown by repressing the major central metabolic dehydrogenases in B. subtilis. |
| CFN97734 | Phytone Phytone appeares to enhance both the sticky materials production and cell growth, suggesting that it plays some role in the increase of sticky materials and cell growth. |
| CFN90281 | Cyclo(Pro-Leu) Cyclo(Pro-Leu) has brine shrimp lethality. |
| CFN90282 | Cyclo(Pro-Ala) Cyclo(Pro-Ala) is a new cell cycle inhibitor. |
| CFN90283 | Cyclo(Leu-Ala) Cyclo(Leu-Ala) is the Diketopiperazine. |
| CFN97735 | Olivetol Olivetol is a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol has antioxidant effects. |
| CFN97736 | Butin Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SOD induction via the PI3K/Akt signaling pathway.Butin against H2O2-induced apoptosis were exerted via blockade of membrane potential depolarization, inhibition of the JNK pathway and mitochondria-involved caspase-dependent apoptotic pathway, enhancing the expression of phosphorylated Akt (active form of Akt), a regulator of OGG1. |
| CFN97737 | (E)-Aldosecologanin (E)-Aldosecologanin is a natural product from Lonicera japonica. |
| CFN97738 | Rehmannic acid Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent uncouplers, abolishing the phosphate uptake, the respiration being inhibited by the former and increased by the latter. |
| CFN90284 | Cyclo(Ile-Ala) Cyclo(Ile-Ala) is a new cell cycle inhibitor. |
| CFN90285 | Cyclo(Hpro-Leu) Reference standards. |
| CFN90286 | Cyclo(Phe-Gly) Cyclo(Phe-Gly) shows weak antagonistic activity against VEGFR2 -CD, it also shows strong inhibitory activity against human cancer cells(KB,KBv200) with LD50 at 6.5 and 11.2 umol/L,respectively. |
| CFN97739 | Isopedicin Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA through its inhibition of cAMP-specific PDE. |
| CFN97740 | Isoscabertopin Isoscabertopin has anticancer activity. |
| CFN97741 | Dihydropashanone Standard reference |
| CFN97742 | Mangiferolic acid Reference standards. |
| CFN90287 | Cyclo(Tyr-Leu) Cyclo(Tyr-Leu) shows cytotoxicity, antifungal,and anticoagulant activities. |
| CFN90288 | Cyclo(Leu-Leu) Cyclo(Leu-Leu) is an efficient supramolecular catalyst. |
| CFN90289 | Cyclo(Ile-Leu) Cyclo(Ile-Leu) shows cytotoxic activity in vitro. |
| CFN97743 | 8-Acetoxypentadeca-1,9Z-diene-4,6-diyn-3-ol Reference standards. |
| CFN97744 | Taxiresinol Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic cell line, KU812. Taxiresinol can protect the hepatocytes from apoptosis via an inhibition of TNF- alpha production by activated macrophages and a direct inhibition of apoptosis induced by TNF- alpha in D-GalN/LPS-treated mice. |
| CFN97745 | Isodeoxyelephantopin Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibiting NF-kappaB activation and NF-kappaB-regulated gene expression. |
| CFN97746 | Enhydrin chlorohydrin Enhydrin chlorohydrin is a natural product from Smallanthus sonchifolius. |
| CFN90291 | Cyclo(Leu-Val) Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain. |
| CFN97747 | 28-Hydroxy-3-oxoolean-12-en-29-oic acid Reference standards. |
| CFN97748 | Cycloheterophyllin Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be used in the research on and prevention of skin photoaging. Cycloheterophyllin exerts a concentration-dependent inhibition of neutrophil cytosolic protein kinase C (PKC) and rat brain PKC by the O2- generation in rat neutrophils, but has no effect on porcine heart protein kinase A (PKA).It also shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation, due to an inhibitory effect on cyclooxygenase. |
| CFN97749 | Hexahydrocurcumin Hexahydrocurcumin has in vitro antioxidant and anti-inflammatory activities, it has potential beneficial effects as a food and/or dietary supplement. Hexahydrocurcumin has cytotoxic effect, may prove useful in cancer prevention, it together with 5-fluorouracil exerts a synergistic effect and may prove chemotherapeutically useful in treating human colon cancer. Hexahydrocurcumin is also an anti-atherosclerogenic agent in humans, can inhibit platelet aggregation in the treatment of human platelet-rich plasma. |
| CFN97750 | Apocynol A Apocynol A is a natural product from Hydrangea macrophylla. |
| CFN90350 | Oxypeucedanin Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. |
| CFN97751 | Adynerin Standard reference |
| CFN97752 | ent-17-Hydroxykaur-15-en-19-oic acid ent-17-Hydroxykaur-15-en-19-oic acid shows cytotoxicity against human prostate (22Rv1, LNCaP), colon (HT29, HCT116, SW480, SW620), and breast (MCF-7) tumor cells at concentrations ranging from 6 to 50microg/mL. |
| CFN97753 | Dodonolide Standard reference |
| CFN97754 | Methyl dodonate A Reference standards. |
| CFN90307 | 1-Acetoxy-5-deacetylbaccatin I Reference standards. |
| CFN90308 | Acetylshikonin Acetylshikonin can effectively inhibit tumor cells, it can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. Acetylshikonin inhibits the production of eicosanoid, is due to the attenuation of cytosolic phospholipase A(2) membrane recruitment via the decrease in [Ca(2+)](i) and to the blockade of cyclooxygenase and 5-lipoxygenase activity. |
| CFN90309 | 9-Aminocamptothecin 9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity.In combination with 9-Aminocamptothecin, one 15-mer peptide (SAYAATVRGPLSSAS) has synergistic cytotoxic effects with 9-Aminocamptothecin both in the cytotoxicity assay and in nude mouse xenograft human tumor models. |
| CFN97755 | Methyl dodonate A acetate Reference standards. |
| CFN97756 | Cryptomeridiol 11-rhamnoside Reference standards. |
| CFN90310 | Anemosapogenin Anemosapogenin shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed. |
| CFN90311 | Apiosylskimmin Apiosylskimmin is a natural product from Angelica gigas. |
| CFN90312 | Aristololactam I Aristololactam I (AL-I), the main metabolite of aristolochic acid I (AA-I), it can lead to renal damage, the cytotoxic potency of Aristololactam I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase 3-dependent pathway. |
| CFN90313 | Artesunate Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.Artesunate has anti-inflammatory activity, can prevent neuroinflammation in BV2 microglia by interfering with NF-κB and p38 MAPK signalling. |
| CFN90314 | Bayogenin Bayogenin, arjunolic acid, hederagonic acid and 4-epi-hederagonic acid are gly-cogen phosphorylase inhibitors with moderate potency. |
| CFN90315 | Breviscapine Breviscapine can reduce the inflammatory response, protect the lungs from inflammatory cascade responses by inhibiting the expression of IL-18 and ICAM-1. Breviscapine inhibits the increased levels of 4-HNE and 8-OHdG, and enhances the antioxidant capacity of cortex tissue. Breviscapine can treat coronary disease, breviscapine injection significantly ameliorates neurologic deficit, reduces infarct volume and water content, and suppresses the levels of NSE in a time-dependent manner, may the mechanism is by up-regulating the expression of Nrf2/HO-1 pathway . |
| CFN90316 | Brucine sulfate Brucine sulfate is a product from Strychnos nux-vomica L. |
| CFN90317 | Capillarisin Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with G0/G1-phase cell cycle arrest and loss in mitochondrial membrane potential.Capillarisin has anti-inflammatory activity, can inhibit LPS-induced inflammation by blocking TLR4-mediated NF-κB and MAPKs activation in BV2 microglia. Capillarisin possesses promising anti-hyperalgesic and anti-allodynic effects through the inhibition of various inflammatory pain signaling. |
| CFN90318 | Catharanthine Tartrate Catharanthine Tartrate is an anti-tumor drug. Catharanthine Tartrate binds with DNA in a mode of groove binding, Se(Ⅳ)can inhibit the binding of Catharanthine Tartrate and DNA. |
| CFN90319 | Chelidonine Chelidonine is a promising model compound for overcoming MDR and for enhancing cytotoxicity of chemotherapeutics, especially against leukaemia cells, its efficacy needs to be confirmed in animal models. Chelidonine may be a potential therapeutic agent against metastasis of invasive human cancer cells, exhibits anti‑migratory and anti‑invasive effects in MDA‑MB‑231 cells, by suppressing COL‑I‑induced integrin signaling, through inhibiting the formation of the IPP complex and subsequent down‑regulation of IPP downstream signaling molecules, such as Akt and ERK1/2. |
| CFN90320 | Cinchonine Cinchonine has antiplatelet effect, mediated mainly through inhibition of Ca2+-influx and protein kinase C pathways in platelets.Dietary Cinchonine with its effects on adipogenesis and inflammation may have a potential benefit in preventing obesity. Cinchonine may be used as an anti-multidrug resistance agent. |
