ChemFaces Product List

Catalog No.	Information
CFN97828	Eicosyl ferulate Standard reference
CFN90400	Vincristine sulfate Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
CFN90401	Vinorelbine Vinorelbine is a semi-synthetic Vinca alkaloid which is currently used in treatment of different cancer types mainly advanced breast cancer (ABC) and advanced/metastatic non-small cell lung cancer (NSCLC). Vinorelbine-loaded SSM can be developed as a new, safe, stable, and effective nanomedicine for the treatment of breast and lung cancers.
CFN90402	Xanthiazone Reference standards.
CFN90403	Xanthiside Reference standards.
CFN90404	Triptophenolide Triptophenolide is a natural product from Tripterygium wilfordii Hook. f.
CFN90405	Cannabisin D Cannabisin D is a natural product from Cannabis sativa L.
CFN90406	Dehydroglaucine Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger.
CFN90407	Dehydrocavidine Dehydrocorydaline has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. Dehydrocorydaline inhibits the elevation of mitochondrial membrane potential and induces ATP depletion in LPS-stimulated macrophages but neither affects basal mitochondrial membrane potential nor ATP content in non-stimulated macrophages.
CFN90408	Glaucine Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IκBα and NF-κB activities.
CFN90409	Militarine Militarine has plant inhibitory effect against the growth of Italian ryegrass, timothy, and B. striata.
CFN90410	Menisdaurin Menisdaurin is a natural product from Flueggea virosa.
CFN90411	Methyl tanshinonate Methyl tanshinonate has antioxidant activity, it can treat psoriasis.
CFN90412	20R-Ginsenoside Rg2 Ginsenoside Rg2 may have a therapeutic potential for type 2 diabetic patients, it suppresses the hepatic glucose production via AMPK-induced phosphorylation of GSK3βand induction of SHP gene expression .Ginsenoside Rg2 can protect H9c2 cells against H2O2- induced injury through its actions of anti-oxidant and anti-apoptosis.20R-Ginsenoside Rg2 inhibits the cytokine interleukin 1 alpha (IL-1α)-induced reduction in gap junction-mediated intercellular communication (GJIC).
CFN90413	Dencichin Dencichine is a haemostatic agent present, it is also a reported neurotoxic agent found in Lathyrus sativus (grass pea seed).
CFN90414	Eburicoic acid Eburicoic acid and TR2 have anti-inflammatory activity, the mechanism is related to the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, they protect the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms. Eburicoic acid has significant anti-liver cancer effects and more distinctive mechanisms.
CFN90415	Worenine Reference standards.
CFN90416	Tetrahydrocoptisine Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression.
CFN90417	7-(2'-Deoxyadenosin-N6-yl)aristolactam I Reference standards.
CFN90418	Cirsilineol Cirsilineol may be potentially useful for treating T-cell-mediated human inflammatory bowel diseases. Cirsilineol alsio has anti-proliferative activity against cancer cells by the induction of apoptosis via the mitochondrial pathway.
CFN90419	4-Hydroxycoumarin 4-Hydroxycoumarin serves as an immediate precursor of 4-hydroxycoumarin (4HC) type anticoagulants (for example, warfarin).
CFN90420	7-Amino-4-methylcoumarin 7-Amino-4-methylcoumarin is more suitable as a substrate for enteropeptidase than GD(4)K-NA.
CFN90421	4-Methylumbelliferone 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM, which has antitumoral and antimetastatic effects. 4-Methylumbelliferone may inhibit the phosphorylation of HAS2 by PKC through the stimulation of O-GlcNAcylation; it also similarly ameliorates hypertriglyceridemia and hyperglycemia partly by modulating hepatic lipid metabolism and the antioxidant defense system along with increasing adiponectin levels.
CFN90422	Amphotericin B Amphotericin B is an antifungal agent. Amphotericin B can regulate inflammatory cytokines in host cells and regulate inflammatory responses in HGEC, it inhibits the A. actinomycetemcomitans-induced phosphorylation of ERK and p38 MAP kinase. Amphotericin B inhibits the A. actinomycetemcomitans-induced production of prostaglandin E2, the inhibition of the PKA signaling pathway can aid in reducing the degree of nephrotoxicity caused by Amphotericin B. Treatment with amphotericin B, particularly in combination with MCSF, increased the number of oligodendrocyte precursor cells and promoted remyelination within lesions.
CFN90423	Asarylaldehyde Reference standards.
CFN90424	Stachyose Stachyose, as prebiotics, can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.Stachyose inhibits Caco-2 cell proliferation and induces apoptosis in a dose-dependent manner. Stachyose with an RS3 carrier has better preventative effects on colitis than Stachyose alone in mice.
CFN90425	Raffinose After treatment with CVGI, Raffinose family oligosaccharide was hydrolyzed effectively to yield galactose and sucrose. AA-PCD resistance in Raffinose-grown cells occurs with a decrease in both ROS production and cytochrome c release as compared to glucose-grown cells en route to AA-PCD.
CFN90426	Mevastatin Mevastatin inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin inhibits the differentiation of TAO derived orbital preadipocytes by blocking PPAR-gamma mRNA expression. Mevastatin induces cell growth inhibition and apoptosis in SACC cells, it triggers the phosphorylation of the EGFR and inhibits the c-Jun N-terminal kinase pathway.
CFN90427	Simvastatin Simvastatin is an FDA-approved cholesterol-lowering medication, it possesses potent anti-inflammatory property and has potent benefits on endothelial and smooth muscle cell-mediated vasomotor responses. Simvastatin rescues Aβ-mediated cerebrovascular and cognitive deficits. Simvastatin reduces burn-induced splenic apoptosis via downregulation of the TNF-α/NF-κB pathway, it induces p65 instability leads to MMP-9 down-regulation in leukemia cells, while it induces JNK1/c-Jun/ATF-2 activation maintains the MMP-2 expression underlying p65 down-regulation.
CFN90428	Tenacissoside H Tenacissoside H has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
CFN90429	L-Theanine L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis. It is known to promote relaxation and improve concentration and learning ability and has neuroprotective effects. L-Theanine heals gastric ulcer and prevents CCl4-induced experimental hepatic cirrhosis in rats by blocking the main pro-inflammatory and pro-fibrogenic signals. L-Theanine can significantly alleviate the adverse oxidative effect.
CFN90430	Kalopanaxsaponin H Kalopanaxsaponin H has antidiabetic activity.
CFN90431	Dihydroberberine Dihydroberberine has anti-tumor activity. It also improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment.
CFN90432	Berberine hydrogen sulphate Reference standards.
CFN90433	Centaureidin Centaureidin augments IFN-gamma promoter activity by approximately four-fold. Centaureidin shows potential vasorelaxant activity. It inhibits dendrite outgrowth from melanocytes by activating Rho, resulting in the inhibition of melanosome transfer from melanocytes to keratinocytes.
CFN90434	Aloin B Dietary supplementation of aloe components (aloin, aloesin and aloe-gel) can ameliorate intestinal inflammatory responses in a 3% dextran sulfate sodium (DSS)-induced ulcerative colitis rat model, in particular, aloesin is the most potent inhibitor. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation.
CFN90435	Hosenkoside K Hosenkoside K is a natural product from impatiens balsamina.
CFN90436	Mogroside VI Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial properties, no-calorie levels related to obesity, and a low glycemic index to help manage blood sugar levels in diabetic patients;mogrosides have the antimicrobial activity and the insulin-stimulating activity, this includes mogroside I, II, III, IV, V, mogroside VI, 11-o-Mogroside V, and Siamenoside I, siraitiflavandiol, rhamnocitrin-3-O-rhamnoside, and kaempferitrin that are the functional groups in these antimicrobial and insulin secretion activities.
CFN90437	Naringin dihydrochalcone Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.
CFN90438	Nepetin-7-glucoside Nepetin-7-glucoside has antioxidant activity in human HL60 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation.
CFN90439	10-Nitro-camptothecin Reference standards.
CFN90440	Prosapogenin A Prosapogenin A has anti-obesity, and immunomodulating effects, it exhibits cytotoxic activity against the cancer cell line K562 in vitro.
CFN90441	Perivine Perivine, vobasine, coronaridine and dichomine show hypotensive and muscle relaxant activity. Perivine may resolve the instability of the retinoblastoma-associated proteins (RbAp48) complex and thus be used in Alzheimer's disease therapy.
CFN90442	Phlorizin dihydrate Phlorizin dihydrate can significantly inhibit oxidative DNA damage.
CFN90443	Picropodophyllotoxin Picropodophyllotoxin shows highly antifeeding and toxic activities against the 3rd-instar larve of Mythimna separate W.and the 4th-instar larvae of Pieris rapae L.and the 3rd-instar larve of Plutella xylostella L.
CFN90444	Plumbagin Plumbagin, a potential natural FOXM1 inhibitor, has anticancer, and anti-fibrotic activies, it inactivates the NF-κB/TLR-4 pathway that is associated with inflammatory reactions, thereby mitigating liver fibrosis. Plumbagin offers significant protective role against DEX-induced cellular damage via regulating oxidative stress, apoptosis, and osteogenic markers.
CFN90445	Polyphyllin C Reference standards.
CFN90446	Polyphyllin E Polyphyllin E has synergistic anticancer effects.
CFN90447	Polyphyllin F Reference standards.
CFN90448	Poncirin Poncirin has anticancer, anti-bacterial and anti-inflammatory activities; it prevents adipogenesis, enhances osteoblast differentiation in mesenchymal stem cellsincreased bone mineral density, and improves trabecular microarchitecture likely reflect increases bone formation and decreases bone resorption in GIO mice. Poncirin inhibits iNOS, COX-2, TNF-alpha and IL-6 expression via the down-regulation of NF-kappaB binding activity.

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